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KMID : 0376219830200040737
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Chonnam Medical Journal
1983 Volume.20 No. 4 p.737 ~ p.743
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A Clinical Analysis of Head Injury and Coagulation disorders
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Abstract
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Coagulation tests(platelet count, prothrombin time, activated partial thromboplastin time, fibrin and fibrinogen degradation product concentration) were done in 35 head injury patients who were admitted to our department of neurosurgery, Chonnam University Medical School Hospital, from April to September in 1983.
Results were found to be correlated with the level of consciousness and with the type of injury.
Blood specimens were taken for coagulation tests within 24 hours after injury. The result were as follows:
1. Results of coagulation tests were abnormal in 22 of 35 patients (62.9%).
2. DIC was considered to be present if three or more of tests were abnormal and was found in 7 of 35 patients.
3. In correlation between the level of consciousness and coagulation tests, the incidence of abnormal results increased as mental ´state became deep, such as 13.6% in GCS>8 and 49.3% in GCS<9
4. As for the type of injury, the incidence of abnormal results were higher in the cases of brain destruction rather than in them of its compression.
5. Especially, results of FDP test were found to be correlated definitely with the degree of head injury and so, the incidence of abnormal results increased proportionally to the level of consciousness as mental state became deep to coma, such as 27.3% in GCS>8 and 84.6% in GCS<9.
In conclusion, results suggested that coagulation tests, especially measurement of FDP, might have significant value in the evaluation of clinical course and prognosis as well as in diagnosis of head injury.
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